Journal Guide

Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world.Launched in December 1997 and published monthly, Molecular Cell defines the field of molecular biology with a relatively small number of significant papers, up to 15 articles per issue. Coverage will extend from structure to human diseases, concentrating on molecular analyses. Topics that will be represented in the first issues include gene expression, RNA processing, replication, recombination and repair, structure, chaperones, receptors, signal transduction, cell cycle, and tumorigenesis.The majority of papers published in Molecular Cell are articles in the format familiar from Cell. However, we will also publish short papers (up to 6 published pages) that make focused contributions on points of general interest. The publication schedule will be rapid: on our regular monthly schedule, publication time should average 6 weeks from acceptance.Visit the Molecular Cell website to find out more - http://www.molecule.org/

Molecular Genetics and Metabolism is a contribution to the understanding of the metabolic basis of disease. The journal publishes articles describing investigations that use the tools of biochemistry and molecular biology for studies of normal and diseased states. In addition to original research articles, occasional minireviews reporting timely advances as well as brief communications and letters to the editor are considered.Research Areas include:• Inherited Metabolic Diseases:- Biochemical studies of primary enzyme defects- Molecular genetic analyses of mutations- Pathogenesis of these disorders, including not only primary but also secondary metabolic alterations• Systems Biology:- Functional integration of biochemical network modules- Moonlighting functions of proteins• Intercellular and Intracellular Metabolic Relationships:- Biochemical interactions between cells- Functional roles of and interactions between subcellular compartments and distinct regions within these cellular spaces, termed microcompartments- Metabolic relations between individual enzymes and pathways• Cellular Catalysts:- Protein and nonprotein catalyst in normal and deranged cellular metabolism- Relationships between the structure and function of catalytic molecules- Interaction of these catalysts with other cellular components• Disease Pathogenesis:- Underlying mechanisms of inherited and acquired diseases- Relationships between genotype and phenotype at the biochemical and molecular levels• Treatment:- Drug, protein and dietary interventions- Transplantation and gene therapy- Multicenter clinical trialsAdvances in nanomedicine, nanopediatrics and nanotechnology are also welcome.

Molecular Genetics and Metabolism Reports is an Open Access journal that publishes molecular and metabolic reports describing investigations that use the tools of biochemistry and molecular biology for studies of normal and diseased states. In addition to original research articles, sequence reports, brief communication reports and letters to the editor are considered.Research Areas include:• Inherited Metabolic Diseases:- Biochemical studies of primary enzyme defects- Molecular genetic analyses of mutations- Pathogenesis of these disorders, including not only primary but also secondary metabolic alterations• Systems Biology:- Functional integration of biochemical network modules- Moonlighting functions of proteins• Intercellular and Intracellular Metabolic Relationships:- Biochemical interactions between cells- Functional roles of and interactions between subcellular compartments and distinct regions within these cellular spaces, termed microcompartments- Metabolic relations between individual enzymes and pathways• Cellular Catalysts:- Protein and nonprotein catalyst in normal and deranged cellular metabolism- Relationships between the structure and function of catalytic molecules- Interaction of these catalysts with other cellular components• Disease Pathogenesis:- Underlying mechanisms of inherited and acquired diseases- Relationships between genotype and phenotype at the biochemical and molecular levels• Treatment:- Drug, protein and dietary interventions- Transplantation and gene therapy- Multicenter clinical trialsAdvances in nanomedicine, nanopediatrics and nanotechnology are also welcome.

Molecular Immunology is primarily devoted to publications concerned with immunological knowledge at the molecular, cellular and functional levels of innate and acquired immunity, including but not limited to:• molecular mechanisms of innate and adaptive immunity phenomena• molecular aspects of immune regulation• cell signalling and activation; cellular receptors and soluble mediators• immunogenomics, immunoproteomics and immunoglycomics• molecular (immuno) therapeutics• immunochemistry• impact of molecular changes at the tissue levelBenefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com

Molecular Metabolism is committed to serving as a platform reporting breakthroughs from all stages of the discovery and development of novel and improved personalized medicines for obesity, diabetes and associated diseases. The journal aims to publish hypothesis driven research of leading scientists paving the way to a better understanding of metabolic physiology, thereby enabling progress toward prevention and ultimately a cure of the metabolic syndrome. Molecular Metabolism reports interdisciplinary science with the potential for transformative impact on today's metabolism research, focusing on translation of major basic research discoveries toward the personalized medicines needed to prevent and cure diabesity and associated diseases tomorrow.

Molecular Oncology highlights new discoveries, approaches, as well as technical developments, in basic, clinical and discovery-driven translational research. Topics include:• Key biological processes such as cell cycle; DNA repair; apoptosis; invasion and metastasis; angiogenesis and lymphangiogenesis; cell signalling and interactive networks; immune response.• Emerging technologies (genomics, proteomics, functional genomics, metabolomics, tissue arrays, imaging), and model systems.•Biomarkers: diagnosis, prognosis, stratification and efficacy.• Cancer genetics, epigenetics, and genomic instability.• Minimal residual disease, pre-malignant lesions.• Cancer micro-environment.• Molecular pathology.• Tumour immunology.• Translational research.• Cancer therapy (target discovery, drug design, immunotherapy, combination therapies, resistance, and individualised treatment).• Chemotherapy, radiotherapy and surgery.• Clinical pharmacology.• Clinical trials, integration of basic science into cancer clinical trials.• Epidemiology and prevention.• Infrastructures (biobanks, databases, genomic resources).A main feature of the Journal is to provide an international forum for debating cancer issues, and for integrating the input of all the stakeholders.Coverage: Reviews, original articles, technical notes, editorials, news & views (commentary, science policy issues, ethical and legal issues, patient organisations, industry needs and alliances, regulatory issues, news items), letters to the editor, conference announcements, advertisements.Submitting Authors:Manuscripts can be submitted to Molecular Oncology at:http://ees.elsevier.com/molonc/

Monthly issues present original applications of biochemistry, biophysics, genetics, and molecular biology juxtaposed with innovative pharmacologic research to elucidate basic problems in pharmacology and toxicology, including areas such as molecular mechanisms involved in drug receptor-effective coupling, xenobiotic metabolism, and antibiotic and anticancer drug action.Molecular Pharmacology is archived in CLOCKSS.

Molecular Phylogenetics and Evolution is dedicated to bringing Darwin's dream within grasp - to "have fairly true genealogical trees of each great kingdom of Nature." The journal provides a forum for molecular studies that advance our understanding of phylogeny and evolution, further the development of phylogenetically more accurate taxonomic classifications, and ultimately bring a unified classification for all the ramifying lines of life. Phylogeographic studies will be considered for publication if they offer EXCEPTIONAL theoretical or empirical advances.The journal encourages articles that are multidisciplinary, especially in areas, such as bioinformatics, computational biology, molecular biology, and organismic biology, that are of interest to the community of systematic and evolutionary biologists. In addition, presentations of new findings on or insights into evolutionary processes and mechanisms as expressed at the molecular level are welcome, as are those that deal with the methodology of reconstructing evolutionary history from molecular data (such as descriptions of new or more powerful computer algorithms for constructing phylogenetic trees from orthologous nucleotide or aminoacid sequences). A deeper understanding of the mechanisms and processes of molecular evolution should lead to more accurate models of molecular evolution, which in turn should facilitate the development of better algorithms for reconstructing evolutionary history from sequence data.Papers based on few taxa, single molecular markers, or that use codon-based methods to test for positive Darwinian selection, but in the absence of experimental evidence that allegedly selected amino acid changes cause an adaptive phenotypic effect, will not be accepted.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com

Molecular Plant is a recently founded international journal that publishes significant findings in plant biology, focusing broadly on cellular biology, physiology, molecular biology, genetics, development, and evolution.The journal features a strong international editorial board and is set to become a top-tier journal in the field, using rigorous review to limit the journal to papers that provide novel insights of high impact. The editors particularly encourage submissions of original research that is highly novel but not necessarily fully-developed. Contributions may comprise Research Articles, Review Articles, Methods, Editorials, and Commentaries.To set the standard for its future, most of the papers published in Molecular Plant's first two years were commissioned by editorial members and published in Special Issues on particularly exciting and important topics in current plant biology. Now that the journal's standard has been established, Molecular Plant now receives large numbers of high-quality unsolicited submissions, which have been published under the heading 'Topics of General Interest' since May 2009.The journal is steadily increasing the proportion of regular submissions published. Plant biology authors are strongly encouraged to submit their best work to the journal. Every effort is made to ensure papers are fully reviewed within four weeks and that all accepted papers are published online in their final format within four weeks of arrival of the finished manuscript at the publisher.Assessment by the China Association for Science and Technology of ‘top journals in China’ (in 2010) rated Molecular Plant one of seven A-class journals. .

Molecular Therapy is the leading journal for research in the areas of gene transfer, vector development and design, stem cell manipulation, development of gene-, peptide- and protein-, oligonucleotide- and cell-based therapeutics to correct genetic and acquired diseases, vaccine development, pre-clinical target validation, safety/efficacy studies, and clinical trials. Available in print and online, Molecular Therapy is dedicated to promoting the sciences in genetics, medicine and biotechnology. Publishing important peer-reviewed research and cutting-edge reviews and commentaries, the journal continues to attract the best material in the field. Molecular Therapy's 2009 impact factor is 6.239*.

methods, technology development, molecular therapy, gene therapy

Molecular Therapy — Nucleic Acids publishes research targeted to the advances in nucleic acid-based therapeutics to treat and/or correct genetic and acquired disease. Subject areas include: development of therapeutics based on nucleic acids and their derivatives, vector development and design for the delivery of RNA-based therapeutics, and applications of gene-modifying agents.

The journal provides a medium for rapid publication of investigations of the molecular biology and biochemistry of parasitic protozoa and helminths and their interactions with both the definitive and intermediate host. The main subject areas covered are:• the structure, biosynthesis, degradation, properties and function of DNA, RNA, proteins, lipids, carbohydrates and small molecular-weight substances • intermediary metabolism and bioenergetics• drug target characterization and the mode of action of antiparasitic drugs • molecular and biochemical aspects of membrane structure and function• host-parasite relationships that focus on the parasite, particularly as related to specific parasite molecules. (Note that studies predominantly focused on the host response (e.g. immunology) are better suited to other journals.) • analysis of genes and genome structure, function and expression • analysis of variation in parasite populations relevant to genetic exchange, pathogenesis, drug and vaccine target characterization, and drug resistance.• parasite protein trafficking, organelle biogenesis, and cellular structure especially with reference to the roles of specific molecules• parasite programmed cell death, development, and cell division at the molecular levelPapers will only be accepted for publication if they fall within these areas, if they contain original and complete work of high scientific quality, and if they are well presented. Papers solely confirming the conserved functions of genes previously studied in other organisms will not be considered.Most downloaded papersBenefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com

Molecular and Cellular Endocrinology was established in 1974 to meet the demand for integrated publication on all aspects related to the biochemical effects, synthesis and secretions of extracellular signals (hormones, neurotransmitters, etc.) and to the understanding of cellular regulatory mechanisms involved in hormonal control.The journal is fulfilling this aim by publishing full-length original research papers, rapid papers, invited reviews, At the Cutting Edge essays, and book reviews.The scope encompasses all subjects related to biochemical and molecular aspects of endocrine research and cell regulation. These include: (1) mechanisms of action of extracellular signals (hormones, neurotransmitters, etc.), (2) interaction of these factors with receptors, (3) generation, action and role of intracellular signals such as cyclic nucleotides and calcium, (4) hormone-regulated gene expression, (5) structure and physicochemical properties of hormones, hormone receptors and other hormone-binding components, (6) synthesis, secretion, metabolism and inactivation of hormones, neurotransmitters, etc. (7) hormonal control of differentiation, (8) related control mechanisms in non-mammalian systems, (9) methodological and theoretical aspects related to hormonal control processes, (10) clinical studies as far as they throw new light on basic research in this field, (11) control of intermediary metabolism at the cellular level, (12) ultrastructural aspects related to hormone secretion and action.Please bookmark this URL: http://www.elsevier.com/locate/mceUS National Institutes of Health (NIH) voluntary posting ("Public Access") policyMolecular and Cellular Endocrinology and Elsevier facilitate the author's response to the NIH Public Access Policy. For more details please see the Guide for authors

Molecular and Cellular Neuroscience publishes original research of exceptional significance from those areas of the neurosciences indicated by the broadest interpretation of the journal's title. In particular, the journal focuses on synaptic maintenance and organization, neuron-glia communication and regenerative neurobiology. As part of the submission process, authors are asked to state why they consider their paper is of such significance.Furthermore, since rapid peer-review and publication of such research is of paramount importance, extended cycles of article revision and re-review will not be entered into; it is anticipated that authors will fully address all referees' comments during the course of a single revision of their original manuscript.US National Institutes of Health (NIH) voluntary posting ("Public Access") policyMolecular & Cellular Neuroscience and Elsevier facilitate the author's response to the NIH Public Access Policy. For more details please see the Guide for authors

MCP - Advancing Biomedical & Biological Sciences wants to capture outcomes from the current revolution in molecular technologies and sciences. The journal has broadened its scope and embraces any high quality research papers, reviews and opinions in areas including, but not limited to, molecular biology, cell biology, biochemistry, immunology, physiology, epidemiology, ecology, virology, microbiology, parasitology, genetics, evolutionary biology, genomics (including metagenomics), bioinformatics, proteomics, metabolomics, glycomics, and lipidomics. Submissions with a technology-driven focus on understanding normal biological or disease processes as well as conceptual advances and paradigm shifts are particularly encouraged. The Editors welcome fundamental or applied research areas; pre-submission enquiries about advanced draft manuscripts are welcomed. Top quality research and manuscripts will be fast-tracked.Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our support pages: http://support.elsevier.com